Table 3 Correlation coefficients between miRNA expression and independent variables in the WEA cohort according to Spearman.

From: Circulating microRNA-197-3p as a potential biomarker for asbestos exposure

 

miR-197-3p

ddPCR

RT-qPCR

Age

− 0.223

− 0.112

Gender

0.215

0.208

Smoking status

0.154

0.127

P/Y

− 0.105

− 0.077

Asbestos exposure

Cumulative exposure

− 0.389*

− 0.197

Years of exposure

− 0.003

0.002

Years since last previous exposure

− 0.140

− 0.085

Asbestos related pathologies

− 0.028

0.047

Other diseases unrelated to asbestos

Musculoskeletal

0.114

0.131

Cardiovascular

− 0.056

− 0.101

Gastrointestinal

− 0.091

− 0.065

Endocrine and diabetes

− 0.256

− 0.120

Respiratory

− 0.091

− 0.049

Neurological

0.129

0.099

Genitourinary

− 0.126

− 0.124

Neoplastic

0.022

0.121

Therapy

0.110

0.051

  1. Correlation coefficients were determined according to the Spearman test. miRNA levels were expressed as copies/µl of analyzed cDNA. Correlations with p < 0.05(*) were considered statistically significant.