Table 1 Top 21 TFs implicated in the SvOV (SARS-CoV-2 vs. other viruses) TRN.

From: Identification of transcriptional regulatory network associated with response of host epithelial cells to SARS-CoV-2

Transcription factors

Percent of target genes (%)

STAT1

5.89

STAT2

2.95

MLX

2.74

EGR4

1.47

RCOR1

1.47

SP140L

1.47

TP53

1.26

RCOR2

1.26

MAX

1.26

ZNF496

1.26

ZNF512B

1.05

SMAD7

1.05

SOX12

1.05

IRF2

1.05

HDX

1.05

EGR1

1.05

SP110

1.05

IRF9

1.05

ZNF143

1.05

NFIX

1.05

ZBTB32

1.05

  1. The TFs are ranked based on the number of differentially expressed target genes identified by InPheRNo. The second column shows the percent of the considered genes that each TF regulates. As a reference for comparison, the average percent of target genes for a TF is only 0.078% in the SvOV network.
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