Table 2 Top 15 kinases identified using foRWaRD for the top TFs in the SvOV network.

From: Identification of transcriptional regulatory network associated with response of host epithelial cells to SARS-CoV-2

Ranked list of kinases (based on top 21 TFs in SvOV network)

Kinase

Ratio score

MYO3A

11.60

JAK3

10.74

VRK3

10.34

ADCK1

9.74

JAK1

8.69

MAP2K5

8.19

BMX

7.97

HIPK4

7.48

JAK2

7.46

MAP3K13

7.34

LCK

6.63

CAMK2B

6.34

MAPK14

6.32

BTK

6.13

MAPK11

6.05

  1. The kinases are ranked based on the ratio of their query set probability score to their background probability score. Any ratio score > 1 implies that the kinase is scored higher using the top TF query set compared to its control, with a higher score reflecting a high degree of network proximity to the query set.