Figure 1 | Scientific Reports

Figure 1

From: Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: the Replica Project

Figure 1

Cytotoxicity of NCI-H292 cells after WS and VP exposure. (A) Exposure under the ISO regimen. Data points are mean ± SD from 10 replicates of WS and VP. There was no significant (p = 0.098) increase in IC50 for VP exposure (11.76 puffs; Log10 = 1.07) versus WS exposure (10.47 puffs; Log10 = 1.02). (B) Exposure under the HCI regimen. Data points are mean ± SD from 16 replicates for WS and 10 replicates for VP. There was a significant (p = 0.046) increase in IC50 for VP exposure (6.22 puffs; Log10 = 0.79) compared to WS (5.14 puffs; Log10 = 0.71) exposure. Abbreviations: HCI, Health Canada intense; ISO, International Organization for Standardization; VP, vapor phase; WS, whole smoke. Graphs were generated with GraphPad Prism 8 software and edited by using GIMP image manipulation program (version 2.10.14).

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