Figure 9 | Scientific Reports

Figure 9

From: Electronic nicotine delivery systems exhibit reduced bronchial epithelial cells toxicity compared to cigarette: the Replica Project

Figure 9

Calculation of IC50 for nicotine released by WS. (A) ISO regimen, showing IC50 of 4.18 μg/mL nicotine (Log10 = 0.62). (B) HCI regimen, showing IC50 of 9.7 μg/ml of nicotine (Log10 = 0.99). Data points are mean ± SD values from four replicates (LAB-A). Biological response data are presented as a function of nicotine concentration in the exposed media. Abbreviations: HCI, Health Canada intense; ISO, International Organization for Standardization; WS, whole smoke. Graphs were generated with GraphPad Prism 8 software and edited by using GIMP image manipulation program (version 2.10.14).

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