Figure 1 | Scientific Reports

Figure 1

From: Competitive endogenous RNA network and pathway-based analysis of LncRNA single-nucleotide polymorphism in myasthenia gravis

Figure 1

The construction and characteristics of a LCEN. (A) An integrative pipeline used to construct the LCEN by merging dysregulated lncRNA-mRNA ceRNA interactions based on the ceRNA hypothesis. (B) The creation of a LCEN network for MG demonstrated pair bonds among lncRNAs, miRNAs, and mRNAs. Blue triangles represent mRNAs, red circles represent miRNAs, green rhombi represent lncRNAs, and lines represent their regulatory interactions. (C) GO annotation of mRNAs that were co-expressed with mRNAs.

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