Figure 7
From: Safe electrophysiologic profile of dexmedetomidine in different experimental arrhythmia models
(A) Impact of acetylcholine (Ach)/ isoproterenol (Iso) and dexmedetomidine (Dex) on atrial APD90 (aAPD90). (B) Effect of Ach/Iso and dexmedetomidine on atrial conduction time. (C) Influence of Ach/Iso and dexmedetomidine on atrial effective refractory periods (aERP). (D) Incidence of atrial fibrillation episodes under baseline conditions, with Ach/Iso and with additional dexmedetomidine, respectively (# = p < 0.05 compared to baseline conditions; * = p < 0.05 compared to sole Ach/Iso treatment).
