Figure 2 | Scientific Reports

Figure 2

From: Transcriptomic adaptation during skeletal muscle habituation to eccentric or concentric exercise training

Figure 2

Training-(in)dependent gene-level responses to acute ECC and CON. (A) Venn diagrams depicting the degree of overlap between genes upregulated (UR) or downregulated (DR) by acute ECC in untrained versus exercise habituated muscle, along with a heatmap illustrating representative enriched GO terms for each corresponding unique/common gene set. Number of genes enriched for a given term are provided within associated boxes of the heatmap. Strength of colour shading depicts magnitude of enrichment significance, given by the negative log10 of that term’s enrichment FDR P-value (with darker shading analogous with a stronger FDR P-value). (B) As with (A), but for genes regulated by acute CON in untrained versus exercise habituated muscle. B1 = initial, unaccustomed exercise bout. B2 = final, post-habituation exercise bout.

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