Table 3 Biochemical analysis of ET-1, cotinine, Il-6, and TNF-α.

From: Smoking cessation reduces systemic inflammation and circulating endothelin-1

Variable

Baseline

EOT

12-Month

Cotinine (ng/mL)

176.8 ± 109.5

45.0 ± 89.9*

74.9 ± 94.3*

ET-1 (pg/mL)

2.3 ± 0.6

1.9 ± 0.6*

2.0 ± 0.8

TNF-α (pg/mL)

7.0 ± 1.6

6.3 ± 1.5*

5.2 ± 2.7*†

IL-6 (pg/mL)

2.19 ± 1.09

1.84 ± 0.75

1.80 ± 1.13

  1. Serum concentrations of cotinine (n = 30) and plasma concentrations of ET-1 (n = 30), TNF-α (n = 30), and IL-6 (n = 28) at baseline, 3-months (end of treatment, EOT), and 12-months (12M) following smoking cessation. Repeated measures ANOVA.
  2. *p < 0.05 compared with BL.
  3. †p < 0.05 with 3M.
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