Table 1 Cell cycle distribution of chondrosarcoma cells 1 h, 4 h, 8 h, and 24 h after 4 Gy X-ray respectively proton IR (n = 5; mean ± SD; n.s. not significant).

From: Activation of efficient DNA repair mechanisms after photon and proton irradiation of human chondrosarcoma cells

 

G0/G1 (%)

S (%)

G2/M (%)

ctrl X-ray

49.23 ± 3.77

23.25 ± 6.08

19.17 ± 3.05

ctrl proton

42.91 ± 1.27

40.90 ± 0.43

16.19 ± 1.01

4 Gy X-ray 1 h

44.15 ± 12.65

31.99 ± 9.14

23.85 ± 4.19

n.s.

n.s.

n.s.

4 Gy proton 1 h

40.30 ± 1.94

43.87 ± 1.99

15.86 ± 2.23

n.s.

n.s.

n.s.

4 Gy X-ray 4 h

41.66 ± 12.24

35.29 ± 11.89

23.04 ± 1.10

n.s.

n.s.

n.s.

4 Gy proton 4 h

26.95 ± 2.83

51.11 ± 1.66

21.94 ± 1.92

p = 0.0003

p = 0.0001

n.s.

4 Gy X-ray 8 h

57.97 ± 9.64

16.56 ± 4.62

25.47 ± 10.09

n.s.

n.s.

n.s.

4 Gy proton 8 h

17.95 ± 3.55

43.57 ± 2.46

38.48 ± 1.95

p < 0.0001

n.s

p < 0.0001

4 Gy X-ray 24 h

52.50 ± 13.53

17.12 ± 5.82

30.38 ± 9.15

n.s.

n.s.

p = 0.029

4 Gy proton 24 h

41.55 ± 0.56

32.28 ± 1.24

26.10 ± 1.60

p < 0.0001

p = 0.0002

p = 0.002

Back to article page