Figure 2 | Scientific Reports

Figure 2

From: Functional and structural analysis of non-synonymous single nucleotide polymorphisms (nsSNPs) in the MYB oncoproteins associated with human cancer

Figure 2

Structural comparison of wild-type MYB family proteins with their mutant forms. (a) 3D model of wild-type MYB protein. (b) Superimposed structures of wild-type MYB protein and its mutant having mutation from Glycine to Serine at position 111. (c) Superimposed structures of wild-type MYB protein and its mutant having mutation from Asparagine to Serine at position 183. (d) 3D model of wild-type MYBL1 protein. (e) Superimposed structures of wild-type MYBL1 protein and its mutant having mutation from Glycine to Serine at position 122. (f) 3D model of wild-type MYBL2 protein. (g) Superimposed structures of wild-type MYBL2 protein and its mutant having mutation from Serine to Cysteine at position 178.This figure was generated using UCSF Chimera 1.15 (https://www.cgl.ucsf.edu/chimera/download.html).

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