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Figure 1

From: Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis

Figure 1

Neutrophil depletion treatment after 15 weeks of high fat-fructose-cholesterol diet (FFC). (a) Mice were fed with FFC diet for 15 weeks and were administered with IgG (FFC + IgG, n = 6) or anti-Ly6G (FFC + anti-Ly6G, n = 6) intraperitoneal injections for 14 days until sacrifice. Control diet was used as a NASH negative control (CD, n = 6). Liver/body weight ratio (b), liver weight (c), body weight (d) and serum alanine transaminase (e) were compared between the mentioned groups with 1-way analysis of variance (ANOVA) followed by the Turkey post hoc test. P < .05 was considered a significant difference. Ly6G lymphocyte antigen 6 complex locus G6D, LW/BW liver/body weight ratio, ALT alanine aminotransferase.

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