Figure 5 | Scientific Reports

Figure 5

From: Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis

Figure 5

Hepatic steatosis, fibrosis and hepatic stellate cell (HSC) activation are ameliorated in NASH resolution induced by diet reversal. Steatosis (a), fibrosis (b) and activated HSC activation (c) were detected via hematoxylin, Sirius Red and α-SMA IHC stainings respectively in paraffin embedded tissue sections. Hydroxyproline levels and mRNA expression of fibrosis-related genes (d) and HSC activation markers (e) were analyzed through RT-qPCR among the control diet, FFC and diet reversal receiving groups. Data was analyzed with ANOVA comparison followed by the Turkey post hoc test.

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