Figure 8

Higher co-localization of Cx43 and Cx30 in endfeet of Cx43^(Δ/−) than Cx43^(+/−) mouse brain. (a) Images showing expression of Cx43 (green) and Cx30 (red) in brain vessels of Cx43^(+/−) and Cx43^(Δ/−) mice. (b) Quantification of the degree of co-localization of Cx43 with Cx30 (m1) and of Cx30 with Cx43 (m2) at perivascular region of Cx43^(+/−) and Cx43^(Δ/−) mice. Note that overlap for each connexin with the other was higher in mice lacking the Cx43 carboxyl terminus. Scale bar: 100 µm.