Table 2 Detailed information of the patients with cytogenetic abnormalities.
Patient no | Gender | Age (years) | EGIL classification | 2016 WHO classification | Gene fusion | Chromosome karyotype | CR | OS (day) |
|---|---|---|---|---|---|---|---|---|
1 | Male | 24 | BAL | MPAL, B-M, NOS | E2A/PBX1 | 46, XY, [9]/43, XY,b (1q), 6q-, -9, -10,11q-,-15,-17,-18,19p-,-21 [1] | Yes | 478+ |
2 | Female | 42 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P210) | 46, XX, t(9;22) (q34;q11) [20] | Yes | 115+ |
3 | Female | 24 | BAL | MPAL, B-M, NOS | Neg | 46, XX, t (2:5) (p21:p15), del (6) (q16-q22), t (9:x) (p24:q21) | Yes | 578 |
13 | Female | 56 | BAL | MPAL, T-B, NOS | Neg | 46, XY, dic(11:22)(q24;q12),del(12)(q22) [7]/46,xx [3] | No | 381 |
15 | Male | 20 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P190) | 46, XY, r (5) (p15q35), t (9; 22) (q34, q11) [14]/46, XY, t (9; 22) (q34; q11) [6] | Yes | 530+ |
16 | Female | 58 | BAL | MPAL, T-M, NOS | SET/CAN | Neg | No | 360 |
19 | Male | 26 | BAL | MPAL, T-B, NOS | Neg | Subtriploid karyotype | Yes | 602+ |
21 | Female | 29 | BAL | MPAL, BCR/ABL+ | BCR/ABL | 46, XX [6]/[CP] 46, XX, 2q+, t (9; 22) (q34; q11), 14p+ [8] | Yes | 579+ |
22 | Male | 25 | BAL | T-ALL | – | 43–47, XY, t (4; 11) (q21; p15), +6, del (6) (q21), del (7), (q21), del (7) (q14), add (9) (p24), add (11) (p15), add (14) (q32), -17, del (17), (p13), +ace [cp6]/46, XY, [14] | No | 83 |
25 | Female | 43 | BAL | MPAL, T-M, NOS | – | 47, XX, +21 [4]/46, XX [2] | Yes | 545+ |
26 | Female | 41 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P210) | – | Yes | 2293+ |
29 | Female | 60 | BAL | B-ALL | Neg | 47, XX, t(8; 13), (q10; p10), +22 [10] | No | 51 |
31 | Male | 50 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P210) | 47, XX, +11 [9]/46, XX, [1] | Yes | 850+ |
32 | Female | 36 | AUL | AUL | Neg | 47, XX, +8 [3] | No | 382 |
36 | Male | 18 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P190) | Neg | Yes | 565+ |
37 | Male | 42 | BAL | MPAL, BCR/ABL+ | BCR/ABL (P190) | 49, XY, t (9; 22) (q34; q11), +10, +21, +der (22) t (9; 22) (q34; q11) [1]/53, idem, M31 + X, +1, +5, +8 [1]/46, xy [18] | No | 731 |
44 | Male | 44 | BAL | MPAL, T-M, NOS | Neg | 46, XY [6]/47, XY, +10 [14] | Yes | 351+ |
45 | Male | 23 | AUL | AUL | Neg | 47, XY, add (2) (q37), +4, t (10;11) (p12;q21), -17, +mar [4]/47, idem, add (2) (q37) [1] /46, XY, [15] | Yes | 141 |
