Figure 4
From: Baseline predictors for subretinal fibrosis in neovascular age-related macular degeneration

Right eye of a patient with a type 2 MNV and questionable development of subretinal fibrosis. Figures show the MNV lesion at baseline (a–c) and after 12 months (d–i). The patient had a small hemorrhage on color fundus photography at baseline (a) and developed questionable subretinal fibrosis (SF) after 12 months visible as faint yellowish subretinal material in (d). The area is colocalized with a fibrovascular pigment epithelial detachment in the SD-optical coherence tomography (OCT) B-scan at month 12 (g). The location of the B-scan is indicated by the green arrow in the infrared en face image (f). The baseline en face OCT angiography image (b) and the quantitative vessel analysis (c) using the Angiotool software is shown and the location of the OCT angiography en face images is indicated by the white dotted square in (a). Microperimetry (e) shows well-preserved retinal function indicated by green dots in the area with presumed fibrosis. Axis orientation (h) and pseudo-SLO PS-OCT imaging (i) do not confirm the presence of fibrosis. Using multimodal imaging the lesion was therefore graded as no fibrosis. Color bar indicates − 90 to + 90° for axis orientation.