Table 4 Microbiological findings by use of the BioFire FilmArray Pneumonia panel plus versus standard microbiological methods in 24 patients with other respiratory tract infections.

Microbes	Other respiratory tract infections (other RTIs)
	Total detections*			Detections deemed^a relevant**
	All methods combined	FAP plus	Standard methods	All methods combined	FAP plus	Standard methods
Viruses	24	24 (100)	20 (83)	24	24 (100)	20 (83)
Influenza A virus	13	13 (100)	13 (100)	13	13 (100)	13 (100)
Human metapneumovirus	3	3 (100)	2 (67)	3	3 (100)	2 (67)
Respiratory syncytial virus	4	4 (100)	3 (75)	4	4 (100)	3 (75)
Coronavirus	2	2 (100)	–	2	2 (100)	–
Parainfluenza virus	0	0 (–)	0 (–)	0	0 (–)	0 (–)
Rhino-/enterovirus	2	2 (100)	2 (100)	2	2 (100)	2 (100)
Bacteria	22	22 (100)	6 (27)	0	0 (–)	0 (–)
H. influenzae	10	10 (100)	4 (40)	0	0 (–)	0 (–)
S. pneumoniae	4	4 (100)	0 (0)	0	0 (–)	0 (–)
M. catarrhalis	3	3 (100)	1 (33)	0	0 (–)	0 (–)
E. coli	2	2 (100)	0 (0)	0	0 (–)	0 (–)
S. aureus	2	2 (100)	1 (50)	0	0 (–)	0 (–)
S. agalactiae	1	1 (100)	0 (0)	0	0 (–)	0 (–)
S. epidermidis	0	–	0 (–)	0	–	0 (–)
K. pneumoniae	0	0 (–)	0 (–)	0	0 (–)	0 (–)
S. marcescens	0	0 (–)	0 (–)	0	0 (–)	0 (–)
P. aeruginosa	0	0 (–)	0 (–)	0	0 (–)	0 (–)
Proteus spp.	0	0 (–)	0 (–)	0	0 (–)	0 (–)
K. oxytoca	0	0 (–)	0 (–)	0	0 (–)	0 (–)
A. calcoaceticus–A. baumanii complex	0	0 (–)	0 (–)	0	0 (–)	0 (–)
E. cloacae complex	0	0 (–)	0 (–)	0	0 (–)	0 (–)
M. pneumoniae	0	0 (–)	0 (–)	0	0 (–)	0 (–)
L. pneumophila	0	0 (–)	0 (–)	0	0 (–)	0 (–)
Other detections	0	–	0 (–)	0	–	0 (–)
C. albicans	0	–	0 (–)	0	–	0 (–)
P. jirovecii	0	–	0 (–)	0	–	0 (–)
Total	46	46 (100)	26 (57)	24	24 (100)	20 (83)

Microbiological findings provided by the syndromic PCR panel (FAP plus) compared to SDs in patients with other RTIs (n = 24). Detections deemed as clinically relevant ^a pathogens are further specified. *Data are shown as number of detections with percentage of the respective microbe’s total detections (All methods combined) in brackets. **Data are shown as number of relevant detections with percentage of the respective microbe’s total relevant detections (All methods combined) in brackets. Statistically significant differences (McNemar’s test, p < 0.05) between the FAP plus and SDs, are marked with bold fonts.
RTI, respiratory tract infection; FAP plus, Biomérieux BioFire FilmArray Pneumonia panel plus; SDs, standard diagnostic methods; –, not applicable; FIA, fluorescent immunoassay.
^aThe clinical relevance of all detected microbes was evaluated retrospectively using pre-specified criteria (Supplementary material, S4).

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