Figure 6
From: Ablation of VLA4 in multiple myeloma cells redirects tumor spread and prolongs survival
LLP2A-Cy5 reports on expression of dimeric VLA4 in primary human multiple myeloma. (A) Percentage of LLP2A + , CD49d + (α4) and CD29 + (β1) on CD138 + CD38 + cells from 12 MM BM patient samples. Dense and open symbols referred to newly diagnosed and relapsed patient samples, respectively. (B) The correlation between percentage of LLP2A + cells and CD29 + cells [Pearson correlation coefficient with r = 0.958 (p < 0.0001)]. (C) The percentage of LLP2A + cells and (D) relative mean fluorescent intensity (RMFI) on different cell types (19 MM PC samples).
