Table 1 Sociodemographic, clinical, and head motion comparisons among PD-non pRBD, PD-pRBD and HC.

From: Disrupted functional connectivity in PD with probable RBD and its cognitive correlates

 

PD-non pRBD (n = 32)

PD-pRBD (n = 27)

HC (n = 30)

Test stat

p-value

Sociodemographic and clinical data

Sex, male, n (%)

21 (65.6)

23 (85.2)

13 (43.3)

10.863a

0.004f,g

Age, y, mean (SD)

64.5 (9.9)

68.8 (9.2)

67.5 (7.7)

1.827b

0.167

Education, y, mean (SD)

12.8 (5.3)

11.4 (5.4)

11.4 (4.0)

1.255c

0.534

Age of onset, y, mean (SD)

58.2 (10.5)

59.2 (9.6)

NA

0.378d

0.707

Disease duration, y, mean (SD)

6.3 (3.6)

8.6 (5.0)

NA

1.977d

0.055

LEDD, mean (SD)

516.6 (277.4)

707.8 (469.2)

NA

336.5e

0.146

MDS-UPDRS-Part III, mean (SD)

15.4 (10.2)

17.1 (8.1)

NA

314.5e

0.228

H&Y stage, n, 1/2/2.5/3/4

6/17/1/6/0

2/11/0/10/1

NA

5.689a

0.224

UPSIT, mean (SD)

18.9 (6.8)

16.8 (6.8)

29.2 (4.3)

39.319c

 < 0.001f,g

RBD-I, symptoms/answers, mean (SD)

0.08 (0.09)

0.56 (0.14)

0.05 (0.07)

59.453

 < 0.001g,h

Mean interframe head motion

Rotation, degrees, mean (SD)

0.051 (0.033)

0.051 (0.030)

0.039 (0.020)

2.215c

0.330

Translation, mm, mean (SD)

0.100 (0.057)

0.095 (0.043)

0.124 (0.058)

2.523b

0.086

Maximum interframe head motion

Rotation, degrees, mean (SD)

0.308 (0.215)

0.327 (0.200)

0.267 (0.165)

0.840c

0.657

Translation, mm, mean (SD)

0.377 (0.190)

0.481 (0.211)

0.502 (0.170)

7.164c

0.028f

  1. PD-non pRBD Parkinson’s disease patients without probable REM sleep behavior disorder, PD-pRBD Parkinson’s disease patients with probable REM sleep behavior disorder, HC healthy controls, y years, LEDD levodopa equivalent daily doses, MDS-UPDRS Movement Disorder Society Unified Parkinson's Disease Rating Scale, H&Y Hoehn and Yahr scale, UPSIT University of Pennsylvania Smell Identification Test, RBD-I Innsbruck REM Sleep Behavior Disorder Inventory.
  2. aChi-squared test.
  3. bAnalysis of variance (ANOVA) test followed by Bonferroni post-hoc test.
  4. cKruskal–Wallis H test followed by Mann–Whitney U test.
  5. dt-test.
  6. eMann–Whitney U test.
  7. fPost-hoc differences between PD-non pRBD and HC (p < 0.05).
  8. gPost-hoc differences between PD-pRBD and HC (p < 0.05).
  9. hPost-hoc differences between PD-non pRBD and PD-pRBD (p < 0.05).
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