Figure 6

Female elastase-treated mice. Combined treatment of elastase and BAPN in female mice resulted in large aneurysms. (a) Similar to the male mice, these aneurysms tended to have a thin, proximal region and a thick, thrombus-laden distal region. (b) In addition, two of the five female mice died before end-of-study. (c) Among the remaining female mice, maximum diameter was significantly larger than that of the males, beginning on Day 21. *p < 0.05 for male and female comparison within each time point.