Figure 7 | Scientific Reports

Figure 7

From: O-ring-induced transverse aortic constriction (OTAC) is a new simple method to develop cardiac hypertrophy and heart failure in mice

Figure 7

Data are expressed as the mean ± standard error of the mean. O-rings had inner diameters of 0.50 mm (OTAC0.50) and 0.45 mm (OTAC0.45). Terminal sacrifice was performed in 4 weeks and 8 weeks after procedures. Relative left ventricular (LV) mRNA levels of Nppa (A), Nppb (B), Acta1 (C), Col1a1 (D), and Col3a1 (E) among groups at 4- and 8-weeks post procedure. Comparison among groups was performed by one-way analysis of variance (ANOVA) with Tukey’s post hoc tests; n = 9–14. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.

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