Table 1 Differentially methylated genes (FDR cutoff of p < 0.05 and Δβ > 0.2) in chorionic villi of miscarriages with trisomy 16.

From: Identification of differentially methylated genes in first-trimester placentas with trisomy 16

Symbol

RefSeq

Product

CpG-island

Δβ

Chr

ZNF804B

NM_181646.2

Zinc-finger protein 804B

True

0.279

7

ANKRD53

NM_024933.2

Ankyrin repeat domain-containing protein 53

True

−0.275

2

TRPV6

NM_018646.2

Transient receptor potential cation channel; subfamily V; member 6

False

−0.268

7

SEC31L2

NM_015490.3

S. cerevisiae SEC31-like 2 isoform a

True

−0.258

10

CCL2

NM_002982.3

Small inducible cytokine A2 precursor

False

−0.233

17

GATA3-AS1

NM_207423.1

GATA3 antisense RNA 1

True

−0.226

10

SLC13A4

NM_012450.2

Solute carrier family 13 (sodium/sulfate symporters); member 4

False

−0.223

7

SLC17A4

NM_005495.1

Solute carrier family 17 (sodium phosphate); member 4

False

−0.221

6

CYSLTR2

NM_020377.2

Cysteinyl leukotriene receptor 2

False

−0.219

13

ZNF683

NM_173574.1

Zinc-finger protein 683

False

−0.216

1

CALCB

NM_000728.3

Calcitonin-related polypeptide; beta

True

−0.215

11

PDZD3

NM_024791.2

Sodium-phosphate cotransporter IIa C-terminal-associated protein 2

False

−0.214

11

CCR8

NM_005201.2

Chemokine (C–C motif) receptor 8

False

−0.210

3

FANCG

NM_004629.1

Fanconi anemia; complementation group G

True

−0.209

9

KRTAP10-8

NM_198695.1

Keratin-associated protein 10–8

False

−0.204

21

BRS3

NM_001727.1

Bombesin-like receptor 3

False

−0.203

X

CCL21

NM_002989.2

Small inducible cytokine A21 precursor

False

−0.202

9

SLC3A1

NM_000341.2

Solute carrier family 3; member 1

False

−0.201

2