Figure 4

Differential expression of proteins in retrospectively group (Group 4). (A) Significant higher expression of ADAMTS9 and SLC16A8 in anti-VEGF non-responder (≥ 5 anti-VEGF injections/year), as compared to responders (≤ 4 anti-VEGF injections/year) in wet AMD patients. (B) APOE expression significantly higher in non-responder (≥ 5 anti-VEGF injections/year) for anti-VEGF AMD patients in comparison to responders (≤ 4 anti-VEGF injections per year). NR: non-responsive wet AMD for anti-VEGF treatment; R: responsive wet AMD for anti-VEGF treatment. Bar is representing SEM; P < 0.05.