Table 1 Comparative analysis of NanoSpike- and NanoNuc-mediated hemagglutination tests.

From: A rapid and affordable point of care test for antibodies against SARS-CoV-2 based on hemagglutination and artificial intelligence interpretation

 

Nucleocapsid CIA (Abbott)

Spike ELISA (EUROIMMUN)

Positive percent agreement (%)

Negative percent agreement (%)

Ig pos, n = 80

Ig neg, n = 108

Ig pos, n = 42

Ig neg, n = 40

NanoSpike

  

41

39

98

98

NanoNuc

59

106

  

74

98

  1. Hemagglutination assays based on serum from COVID-19 convalescent and control patients was performed using NanoSpike and NanoNuc and directly compared to results obtained from the Nucleocapsid CIA (Abbot) and Spike ELISA (EUROIMMUN), respectively. Hemagglutination assay controls, i.e. NanoControl and NanoLink were included to aid visual test interpretation.