Figure 2
From: Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization
Rotenone dose–response study. Vehicle or rotenone (1 mg/kg/day or 3 mg/kg/day) was administered for 6 days via a subcutaneous osmotic minipump. Assessments of locomotion, rearing and stereotypy were conducted on days 1, 3 and 6. Locomotion and rearing behaviors were significantly decreased in rats treated with 3 mg/kg rotenone on days 3 and 6. There was no effect of rotenone on stereotypy behaviors. One-way ANOVA with a Dunnett’s post hoc test, *p < 0.05, **p < 0.01.
