Figure 7
From: Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization
Onset phase motor effects of rotenone administration time on the expression of behavioral sensitization after a methamphetamine (meth) acute challenge. Administration of rotenone to saline-yoked rats on R28 reduced horizontal beam breaks, vertical beam breaks, vertical time, vertical movement number, stereotypy count, and stereotypy time compared to R0 saline/rotenone rats. Compared to R14 saline/rotenone rats, R28 rats had reduced horizontal beam breaks, vertical beam breaks, stereotypy count, and stereotypy number. R14 administration reduced vertical movement number in R14 saline/rotenone rats compared to R0 saline/rotenone rats. R0 meth/rotenone rats had reduced horizontal beam breaks, total distance traveled, and stereotypy count compare to R0 saline/rotenone rats. R14 meth/rotenone rats had increased horizontal beam breaks, total distance traveled, and stereotypy count compared to R0 meth/rotenone rats. R28 meth/rotenone rats had reduced horizontal beam breaks, vertical movement number, and stereotypy count compared to R14 meth/rotenone rats and lower vertical beam breaks, vertical movement number, and stereotypy count compared to R0 meth/rotenone rats. The first bar graph contains the samples size for each treatment group.
