Table 3 Saline/vehicle rats behavioral outcomes (mean ± SEM).

From: Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization

 

R0 (n = 8)

R14 (n = 9)

R28 (n = 4)

Onset of meth effect

Horizontal activity

916 ± 64

904 ± 62

707 ± 26

Total distance

413 ± 28

489 ± 35

493 ± 54

Vertical activity

227 ± 32

199 ± 30

164 ± 35

Vertical time

80 ± 23

52 ± 10

54 ± 16

Vertical movement no

35 ± 4

29 ± 3

29 ± 3

Stereotypy count

340 ± 21

348 ± 30

457 ± 51

Stereotypy time

60 ± 4

60 ± 4

63 ± 6

Stereotypy no

49 ± 2

50 ± 2

49 ± 2

Peak meth effect

Horizontal activity

904 ± 58

859 ± 45

827 ± 95

Total distance

385 ± 21

376 ± 22

369 ± 33

Vertical activity

263 ± 26

216 ± 30

199 ± 42

Vertical time

67 ± 10

57 ± 8

54 ± 13

Vertical movement no

39 ± 3

33 ± 3

34 ± 5

Stereotypy count

311 ± 19

344 ± 19

368 ± 25

Stereotypy time

56 ± 4

62 ± 3

64 ± 6

Stereotypy no

48 ± 1

50 ± 1

47 ± 1

  1. Verification that the controls are similar across all time points. Capacity of meth to alter motor activity is the same regardless of when the animals received the vehicle.
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