Figure 2

Otoferlin is increased in untreated JDM PBMCs. RT-qPCR confirmation of increased expression of otoferlin in JDM. The x-axis shows the disease status of the samples, which includes control (n = 13), untreated JDM (n = 11), or inactive JDM (n = 7). The y-axis shows the mean and standard deviation of gene expression relative to controls. The untreated samples have significantly increased otoferlin expression compared to both control and inactive PBMCs.