Table 1 Baseline characteristics of the study population in the association analysis.

From: A multi-omics study of circulating phospholipid markers of blood pressure

 

Discovery

Replication

CROATIA-Vis

ERF

NSPHS

ORCADES

MICROS

N

710

717

678

681

1,185

Age (y)

56.6 (15.6)

51.9 (14.2)

47.1 (20.8)

57.0 (13.9)

45.7 (16.4)

Sex (% women)

57.40

59.00

53.2

57.9

56.0

Body mass index (kg/m2)

27.4 (4.3)

27.0 (4.4)

26.4 (4.8)

27.7 (4.8)

25.6 (4.8)

HDL-C (mmol/L)

1.10 (0.16)

1.29 (0.36)

1.60 (0.41)

1.57 (0.42)

1.68 (0.38)

TC (mmol/L)

5.12 (0.99)

5.67 (1.08)

5.86 (1.33)

5.56 (1.14)

5.87 (1.19)

Lipid-lowering medication use (%)

3.00

16.60

10.47

4.10

5.47

Systolic blood pressure (mmHg)

137.8 (24.45)

141.7 (22.0)

122.8 (18.6)

130.1 (18.46)

132.6 (20.5)

Diastolic blood pressure (mmHg)

80.5 (11.47)

80.6 (10.24)

74.1 (7.8)

76.0 (9.6)

79.6 (11.3)

Antihypertensive medication use (%)

24.1

25.2

20.5

39.1

14.6

Type 2 diabetes (%)

4.2

6.0

4.1

2.8

3.1

  1. Values are mean (SD) or percentages. N refers to the largest sample size used in this study.