Figure 5

Distribution of RMS of distortion and MI between b = 0 s/mm² and T2-weighted images. (A) Distortion for lesions across all stations (black) as well as the distribution within specific imaging Stations (red, blue, and yellow). Distortion was estimated by calculating the RMS of the values in the distortion map that correspond to the lesion annotation and immediately surrounding areas (see Eq. (1)). (B) Change in MI values between the DWI b = 0 s/mm² and T2-weighted images after DisCo. A value larger than 0 indicates improved agreement between DWI b = 0 s/mm² and T2-weighted images. Again, we plot the distribution for all lesions as well as the breakdown for different Stations. (C) For illustrative purposes, we categorized lesions into three distinct anatomic groups: Vertebra, Pelvis, and Other. The Other category represents lesions in bones such as the clavicle, sternum, and femur. The distribution for distortions for each anatomic group is plotted. (D) Change in MI values between the DWI b = 0 s/mm² and T2-weighted images after DisCo broken down by anatomic group. DisCo led to consistent increases in similarity between DWI b = 0 s/mm² and T2-weighted images. RMS root mean square, MI mutual information.