Table 1 Performance comparison between a flow cytometry-based S immunoassay and two commercially-available SARS-CoV-2 chemiluminescent immunoassays.
Assays under comparison (no. of specimens) | Flow cytometry SARS-CoV-2 S assay result (IgG/IgA/IgG + IgA) | Liaison® SARS-CoV-2 TrimericS IgG assay | ||
---|---|---|---|---|
Positive | Negative | Positive | Negative | |
Positive by Roche Elecsys® Anti-SARS-CoV-2 S (175) | 168/170/172 | 7/5/3 | 151 | 17 |
Negative by Roche Elecsys® Anti-SARS-CoV-2 S (42) | 4/7/7 | 38/35/35 | 1 | 41 |
Positive by Liaison® SARS-CoV-2 TrimericS IgG assay (154) | 150/152/153 | 4/2/1 | – | – |
Negative by Liaison® SARS-CoV-2 TrimericS IgG assay (61) | 20/23/24 | 41/38/37 | – | – |