Figure 5

Identity by Descent reveals subtle differences among identical barcode samples separated in time. (A) Relationship between identical barcode parasites (measured by IBS) and IBD with time. Percent of whole genome relatedness by IBD, color-coded by barcode identity (IBS), identical or different. (B) Relationships between 17 specific identical barcode haplotypes by household, year, and IBD, determined from whole genome sequencing. Years are shown on the X axis. Colored circles represent individual parasites from haplotypes that are color coded according to barcode haplotype. Pie charts and percentages shown represent percent IBD relative to the pairwise comparison to the initial isolate, as defined temporally.