Figure 1 | Scientific Reports

Figure 1

From: RETRACTED ARTICLE: Glycyrrhizic acid ameliorates submandibular gland oxidative stress, autophagy and vascular dysfunction in rat model of type 1 diabetes

Figure 1

Haematoxylin and eosin-stained SMG showing parenchymatous structure with acini (asterisks) and interlobular ducts (arrows) with prominent granular convoluted ducts (GCD) in control group (A). Diabetic group showed vacuolation in both acini and GCD, with stagnation of secretions (curved arrows) (B,C). GA treated group (D) revealed an ameliorative effect by reversing the diabetes impact with minimal atrophy and vacuolations. Similarly, in semithin sections of diabetic SMG (F) obvious loss of secretory granules in acinar cells and disruption of acinar and ductal structures were found in addition to vacuolation and nuclear changes, the changes were reduced by GA application (G) that restored almost normal structure resembling control group (E) (H&E, × 20; Semithin sections TB stain, × 20).

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