Figure 6

Lipid Metabolic Gene Expression in Eyecup and Neural Retinas of 2.5-month-old Heterozygous and Homozygous Tmem135 Mutant Mice. Quantitative PCR analysis of lipid metabolic transcription factors (Srebf2 and Srebf1c) and lipid synthesis genes (Acaca, Fasn, and Scd1) in the (A) eyecups and (B) neural retinas of 2.5-month-old male Tmem135^FUN025/+ (FUN025/ +) and Tmem135^{FUN025/FUN025} (FUN025/FUN025) mice. Numbers in brackets denote number of mice used in experiment. Each dot represents each individual sample. * and ** indicates a P < 0.05 and P < 0.01 significance by Student’s T-test.