Table 3 Pathway analysis using overrepresentation analysis (ORA) on genes significantly-affected in both Tmem135FUN025/FUN025 versus WT eyecup RNA-Seq and GSE29801 and GSE135092 datasets*.
From: A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups
Description | Enrichment ratio | FDR |
|---|---|---|
WP4346: Cholesterol metabolism | 26.40 | 7.41 × 10–7 |
GO:0016126: Sterol biosynthetic process | 37.99 | 1.80 × 10–3 |
GO:0016125: Sterol metabolic process | 18.16 | 1.81 × 10–3 |
GO:0008610: Lipid biosynthetic process | 7.16 | 1.81 × 10–3 |
GO:0006633: Fatty acid biosynthetic process | 17.35 | 1.81 × 10–3 |
mmu01212: Fatty acid metabolism | 21.95 | 9.41 × 10–3 |
