Table 4 Clinical presentation in suckling mice infected with ZIKV or DENV.
Challenge | Vaccine | No. of mice | Symptom | ||
|---|---|---|---|---|---|
Feeble (%) | Staggering march (%) | Death (%) | |||
PBS | PBS | 5 | 0 (0/5) | 0 (0/5) | 0 (0/5) |
Env_M | 5 | 0 (0/5) | 0 (0/5) | 0 (0/5) | |
Env_Z | 5 | 0 (0/5) | 0 (0/5) | 0 (0/5) | |
African ZIKV strain (MR766) | PBS | 5 | 100 (5/5) | 0 (0/5) | 100 (5/5) |
Env_M | 5 | 100 (5/5) | 0 (0/5) | 100 (5/5) | |
Env_Z | 5 | 100 (5/5) | 0 (0/5) | 100 (5/5) | |
Asian ZIKV strain (PRVABC59) | PBS | 5 | 100 (5/5) | 100 (5/5) | 100 (5/5) |
Env_M | 5 | 40 (2/5) | 0 (0/5) | 40 (2/5) | |
Env_Z | 5 | 40 (2/5) | 20 (1/5) | 20 (1/5) | |
DENV-2 | PBS | 5 | 80 (4/5) | 0 (0/5) | 60 (3/5) |
Env_M | 5 | 20 (1/5) | 0 (0/5) | 20 (1/5) | |
Env_Z | 5 | 20 (1/5) | 0 (0/5) | 20 (1/5) | |
