Table1 General characteristics of the eligible studies included in the meta-analysis.
Study | Country | Age (years) | Design | Number of eyes | OCTA device | Scan size (mm2) | Primary outcomes | Diagnostic criteria |
|---|---|---|---|---|---|---|---|---|
Goker et al.16 | Turkey | 37.5 ± 14.3 39.2 ± 14.9 | Cross-sectional study | BD Cases: 22 Controls: 28 | Optovue | 6 × 6 in macular | Macular whole enface superficial and deep VD, Foveal superficial and deep VD, Parafoveal superficial and deep VD, Superficial FAZ | ISGBD |
Çömez et al.17 | Turkey | 39.81 ± 8.93 41.21 ± 9.87 | Case–control study | BD Cases: 42 Controls: 40 | Optovue | 6 × 6 in macular | Macular whole enface superficial and deep VD, Superficial and Deep FAZ | ISGBD |
Türkcü et al.18 | Turkey | 33.8 ± 4.51 32.6 ± 4.06 | Case–control study | BD Cases: 60 Controls: 62 | Optovue | 3 × 3 in macular | Macular whole enface superficial and deep VD, Foveal superficial and deep VD, Superficial and Deep FAZ | ISGBD |
Karalezli et al.19 | Turkey | 38.50 ± 14.30 40.20 ± 14.10 | Case–control study | BD Cases: 56 Controls: 50 | Optovue | 6 × 6 in macular | Macular whole enface superficial and deep VD, Foveal superficial and deep VD, Parafoveal superficial and deep VD | ISGBD |
Emre et al.20 | Turkey | 39.44 ± 13.56 38.1 ± 6.76 | Case–control study | BD Cases: 26 Controls: 30 | Optovue | 6 × 6 in macular | Macular whole enface superficial and deep VD, Parafoveal superficial and deep VD | ISGBD |
Accorinti et al.28 | Italy | 38.7 ± 13.2 35.7 ± 7.8 | Cross-sectional study | BD Cases: 15 Controls: 15 | Zeiss | 6 × 6 in macular | Macular whole enface superficial and deep VD | ISGBD |
Koca et al.29 | Turkey | 40.54 ± 9.4 41.59 ± 8.9 | Case–control study | BD Cases: 94 Controls: 53 | Optovue | 3 × 3 in macular | Macular whole enface superficial and deep VD, Parafoveal superficial and deep VD | ISGBD |
Aksoy et al.30 | Turkey | 38 ± 7.1 37 ± 8.2 | Case–control study | BD Cases: 35 Controls: 30 | Optovue | 6 × 6 in macular | Foveal superficial and deep VD, Parafoveal superficial and deep VD, Superficial and Deep FAZ | ISGBD |
Eser-Ozturk et al.31 | Turkey | 35.7 ± 11.65 40.1 ± 9.08 | Cross-sectional study | BD Cases: 42 Controls: 38 | Topcon | 3 × 3 in macular | Parafoveal superficial and deep VD | ISGBD |
Smid et al.32 | Netherland | 49.5 ± 12.12 44 ± 13 | Cross-sectional study | BD Cases: 46 Controls: 22 | Heidelberg | 6 × 6 in macular | Parafoveal superficial and deep VD | ISGBD |
Cheng et al.33 | China | 38.7 ± 9.5 37.5 ± 6.5 | Case–control study | BD Cases:19 Controls: 25 | Optovue | 3 × 3 in macular | Macular whole enface superficial and deep VD, Superficial and Deep FAZ | ISGBD |
Yilmaz et al.34 | Turkey | 38.05 ± 11.52 39.6 ± 9.6 | Cross-sectional study | BD Cases:40 Controls: 30 | Optovue | 6 × 6 in macular | Foveal superficial and deep VD, Parafoveal superficial and deep VD, | ISGBD |
Pei et al.35 | China | 29.0 (26.0, 36.0) 29.0 (27.0, 40.75) | Case–control study | BD Cases:102 Controls: 124 | Optovue | 3 × 3 in macular | Parafoveal superficial and deep VD | ISGBD |
