Table 5 Processing speed: Hedge’s g effect sizes for each test, in descending order.

From: Systematic review and meta-analysis of cognitive impairment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Test name

N studies

N CFS

N controls

Hedges'g

S.E

95% CI

p value

Q

p

I2 (%)

Study references

Symbol (WAIS)

4

117

116

− 0.70

0.13

− 0.960 to − 0.436

0.0001

2.63

0.45

0.00

Michiels et al.40, Neu et al.42,43, Vercoulen et al.54

Symbol digit modalities test

4

90

75

− 0.59

0.16

− 0.898 to − 0.276

0.0001

1.61

0.66

0.00

Claypoole et al.15, Fiedler et al.24, Krupp et al.30, Lawrie et al.31

Stroop

Colors/words cotation 1

2

71

40

− 0.82

0.21

− 1.224 to − 0.412

0.0001

0.00

0.98

0.00

Marshall et al.35, Robinson et al.44

Colors/words cotation 2

2

58

58

− 0.76

0.19

− 1.134 to − 0.389

0.0001

0.76

0.38

0.00

Fiedler et al.24, Metzger et al.59

Colors

4

117

86

− 0.23

0.15

− 0.524 to 0.058

0.117

27.01

0.00

88.89

Claypoole et al.15, Marshall et al.35, Ray et al.60, Robinson et al.44

Words

4

117

86

− 0.23

0.15

− 0.520 to 0.062

0.123

26.17

0.00

88.54

Claypoole et al.15, Marshall et al.35, Ray et al60, Robinson et al.44

TMT A

9

285

225

0.40

0.09

0.222–0.578

0.0001

16.22

0.04

50.68

Claypoole et al.15, De Luca et al.21, Krupp et al.30, Lawrie et al.31, Michiels et al.40, Michiels et al.39, Robinson et al.44, Tiersky et al.52, Vercoulen et al.54

  1. WAIS Wechsler adult intelligence scale, TMT trail making test, ME/CFS myalgic encephalomyelitis/chronic fatigue syndrome, N number.