Table 2 Serum biochemical parameters in the studied groups on the 90th day.

From: Safety assessment of genetically modified rice expressing Cry1Ab protein in Sprague–Dawley rats

 

Males

Females

 

MA

MB

MC

FA

FB

FC

GLUC (mg/dl)

233.39 ± 59.1

260.68 ± 40.64

254.39 ± 39.85

202 ± 33.99

198.42 ± 20.15

165.2 ± 36.88

BUN (mg/dl)

52.05 ± 7.56

46.53 ± 4.07

57.17 ± 9.38

52.85 ± 6.66

52.32 ± 7.13

62.4 ± 7.95

CREA (mg/dl)

0.85 ± 0.05

0.85 ± 0.05

0.82 ± 0.04

0.82 ± 0.06

0.84 ± 0.06

0.78 ± 0.05

TG (mg/dl)

49.95 ± 15.46

69.37 ± 40.3

47.33 ± 18.6

75.85 ± 23.81

73.95 ± 33.47

63.18 ± 29.6

Chol (mg/dl)

60.9 ± 9.2

56.95 ± 6.19

57.72 ± 9.46

66.35 ± 10.24

73.05 ± 10.2

69 ± 9.28

HDL (mg/dl)

35.85 ± 5.28

34.58 ± 6.41

35.61 ± 6.8

42.85 ± 7.67

46.82 ± 6.81

44.47 ± 7.79

ALT (IU/L)

76.1 ± 20.15

60.95 ± 11.67*

85.56 ± 21.96

73.95 ± 14.65

58.17 ± 14.96*

83.07 ± 18.23

AST (IU/L)

104.45 ± 18.8

104.37 ± 25.66

113.94 ± 13.82

118 ± 26.55

100.72 ± 17.52

134.47 ± 50.23

Ca (mg/dl)

9.57 ± 1.8

9.92 ± 0.96

9.71 ± 1.03

10.14 ± 0.44

10.14 ± 0.62

9.85 ± 0.56

Bili (mg/dl)

0.3 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

0.3 ± 0.0

TP (mg/dl)

6.87 ± 0.7

6.5 ± 1.41

6.51 ± 1.7

7 ± 0.83

7.16 ± 0.62

7.01 ± 0.98

ALB (mg/dl)

2.91 ± 0.21

2.91 ± 0.21

2.85 ± 0.24

3.06 ± 0.27

3.24 ± 0.37

3.24 ± 0.37

LDH (mg/dl)

244.05 ± 354

271.33 ± 394.7

182.29 ± 40.96

269.88 ± 169.79

196.33 ± 72.09

190.54 ± 105.98

UA (mg/dl)

2.27 ± 1.89

1.9 ± 0.65

2.04 ± 0.68

2.03 ± 0.56

2.81 ± 0.88

2.44 ± 1.06

  1. Each value is presented as mean ± SD. MA: male rats with Tarom molaii rice feeding, MB: male rats with GM Bt rice feeding, MC: male rats with standard feeding, FA: female rats with Tarom molaii rice feeding, FB: female rats with GM Bt rice feeding, FC: female rats with standard feeding. Gluc: glucose , BUN: blood urea nitrogen, CREA: creatinine, TG: triglyceride, Chol: cholesterol, HDL: high density lipoproteins, ALT: alanine aminotransferase, AST: aspartate aminotransferase, Ca: calcium, Bili: bilirubin, TP: total protein, ALB: albumin, LDH: lactate dehydrogenase, and UA: uric acid. No significant differences was observed in all groups but the ALT with the p value < 0.05.
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