Table 2 Summary of articles in classification of breast tumour.

From: Classification of malignant tumours in breast ultrasound using unsupervised machine learning approaches

References

Topic

Modality

Strategies

Sample Size

Performances

Issues

Choi et al.34

Effect of a deep learning framework-based computer-aided diagnosis system on the diagnostic performance of radiologists in differentiating between malignant and benign masses on breast ultrasonography

US

1. Deep Learning (GoogLeNet)

173 benign and 80 malignant breast messes

Sensitivity: 85.0%

Specificity: 94.0%

1, 2

Zhou et al.31

Classification of benign and malignant breast tumours in ultrasound images with posterior acoustic shadowing (PAS) using half-contour features

US

1. Disk expansion (DE) segmentation

2. Half-contour detection of PAS: tumour circularity (TC) and standard deviation of degree (SDD)

40 cases with PAS / 10 cases without PAS

Sensitivity: 72%

Specificity: 76%

AUC: 0.78

 

Becker et al.23

Classification of breast cancer in ultrasound imaging using a generic deep learning analysis software

US

1. Deep learning-based image software

(ViDi Suite v 2.0)

82 patients with malignant / 550 with benign lesions

Sensitivity: 80.4%

Specificity: 84.2%

AUC: 0.84

1

Ciritsis et al.32

Automatic classification of ultrasound breast lesions using a deep convolutional neural network

US

1. Deep Learning (dCNN)

40 patients

Sensitivity: 92.1%

Specificity:76.0%

AUC: 83.8

1

Byra et al. 38

Classification of breast lesions using segmented quantitative ultrasound maps of homodyned K distribution parameters

US

1. Homodyned K distribution maps

2. Markov random field model

32 malignant breast tumours /

71 benign masses

Sensitivity: 76.8%

Specificity: 75.8%

AUC: 0.84

2, 3, 6

Silva et al.29

Breast tumour classification in ultrasound images using neural networks with improved generalisation methods

US

1. Neural network

2. 22 mixed features

50 malignant and 50 benign tumours

Sensitivity: 97%

Specificity: 96%

AUC: 0.98

2, 3

Cai et al. 39

Robust phase-based texture descriptor for classification of breast ultrasound images

US

1. Phase congruency detection

2. Texture-based feature extraction

3. SVM

69 benign and 69 malignant cases

Sensitivity: 83.4%

Specificity: 85.4%

AUC: 0.86

2, 3

Ara et al.27

Bimodal multiparameter-based approach for benign–malignant

Classification of breast tumours

US / UE

1. Genetic Algorithm

170 patients

(56 malignant lesions and 145 benign cases)

Sensitivity: 89.3%*

Specificity: 80.1%*

AUC: 0.91*

2, 3

Moon et al. 40

The adaptive computer-aided diagnosis system based on tumour sizes for the classification of breast tumours detected at screening ultrasound

US

1. Quantitative morphological and textural features

2. Linear logistic regression

156 tumours

(78 benign and 78 malignant)

Sensitivity: 85.4%

Specificity:77.8%

AUC: 0.86

2, 3

Singh et al. 30

Fuzzy cluster based neural network classifier for classifying breast tumours in ultrasound images

US

1. Fuzzy c-means clustering / back-propagation artificial neural network

2. SVM

178 patients and mixed with open data

(88 benign / 90 malignant)

Sensitivity: 94.7%

Specificity: 93.6%

AUC: 0.94

2, 3, 5, 6

Jain et al. 28

Texture ratio vector technique for the classification of breast lesions using SVM

US

1. Texture feature: inside the lesion (IAI) and upper side of lesion (UAI)

2. Statistical texture: 7 features

3. SVM

117 images (45 benign and 72 malignant) from open data

Overall classification accuracy: 86.6%

2, 3, 5, 6

  1. US: ultrasound, UE: ultrasound elastography, CDUS: colour-Doppler flow imaging ultrasound, SMI: superb microvascular imaging ultrasound.
  2. *: Report the performance using B-mode US image only.
  3. Issues: 1 Not based on machine learning strategies2, Using semi-segmentation or contour pre-processing to labelling the tumour region3 , Feature extracted from only partial US image5, Unspecified all cases were tissue-proved6, Unspecified ultrasound system model/manufacturer.