Table 2 AUC values for classifying each disease type.

From: Aqueous autotaxin and TGF-βs are promising diagnostic biomarkers for distinguishing open-angle glaucoma subtypes

Comparison

LASSO (ATX, TGF-β1, TGF-β2, and TGF-β3)

P value*

LASSO (ATX and TGF-β3)

P value*

P value†

POAG and normal

0.675

< 0.001

0.607

< 0.001

0.231

SOAG and normal

0.729

< 0.002

0.747

< 0.002

0.768

XFG and normal

0.966

< 0.003

0.967

< 0.003

0.898

POAG and SOAG

0.670

< 0.004

0.694

< 0.004

1.00

POAG and XFG

0.913

< 0.005

0.860

< 0.005

0.768

SOAG and XFG

0.834

< 0.006

0.854

< 0.006

0.196

  1. P values with * means the significance of the AUC value. P values with † shows the results of the comparisons of AUC values between LASSO (ATX, TGF-β1, TGF-β2, and TGF-β3) and LASSO (ATX and TGF-β3).
  2. AUC, area under the receiver operating characteristic curve; POAG, primary open-angle glaucoma; SOAG, secondary open-angle glaucoma; XFG: exfoliation glaucoma; LASSO, least absolute shrinkage and selection operator; ATX, autotaxin; TGF-β, transforming growth factor-beta.
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