Figure 3
Comparison of the signal quality provided by edge (green) and center (red) sites of the 128-channel NeuroSeeker silicon probe. (a) Probability density functions estimated from the amplitude of samples recorded in the 500–5000 Hz frequency range (n = 10 recordings). Probability values lower than 10–9 are not shown. (b) Cumulative distributions of amplitudes calculated in the negative amplitude range. (c) Reverse cumulative distributions calculated in the positive amplitude range. Green shaded areas in (b) and (c) indicate amplitudes with significantly higher numbers of edge samples. Arrows mark the maximal amplitude for edge significance in the negative range (− 10 µV; below this amplitude 8.70% of all negative samples were recorded on edge sites and 8.64% on center sites) and the minimal amplitude in the positive range (10 µV; above this amplitude 9.02% of all positive samples were recorded on edge sites and 8.92% on center sites). (d) Estimated in vivo noise level. (e) Single unit yield (n = 1052). (f) Peak-to-peak amplitude of the averaged single unit spike waveforms. (g) Isolation distance of the single unit clusters. Note that most data are plotted on a logarithmic scale. Mann–Whitney U test was used in (d–g). ***p < 0.001.
