Figure 6
Presence of mature adipocytes in wound beds. (a) H&E staining of MSTC-treated wound at 1 week. Many adipocyte-like structures were seen within the wound bed (solid arrow) and outside the epidermal surface (dotted arrow). (b) MSTC-treated wound at 2 weeks, showing adipocyte-like structures still present in wound bed (arrow). (c) Fewer adipocyte-like structures were also present in some control wounds (arrow). (a–c) Scale bars = 1 mm. (d) IHC staining for the adipocyte marker FABP4 (red). (e) Adipocyte-like structures outside of the epidermal surface (dotted arrow in a) did not retain FABP4 expression. (d,e) Scale bar = 100 μm. (f) MSTC-treated wounds had higher density of FABP4+ adipocytes than control wounds at both time points. **p \(\le \) 0.005.
