Table 1 Region of interest-based volumes (expressed in cm3) and results of ANOVA for intergroup comparisons after normalization against total intracranial volume.

From: Texture-based markers from structural imaging correlate with motor handicap in Parkinson’s disease

 

Healthy controls (N = 32)

Patients with early-stage PD (N = 39)

Patients with late-stage PD (N = 37)

p

TIV

1193.91 ± 98.50

1184.51 ± 154.55

1155.85 ± 160.15

 

SN (right)

0.144 ± 0.018

0.138 ± 0.02

0.130 ± 0.013

0.12

SN (left)

0.142 ± 0.022

0.128 ± 0.016

0.125 ± 0.020

0.08

Putamen (right)

4.51 ± 0.62

4.50 ± 0.62

4.12 ± 0.96

0.11

Putamen (left)

4.57 ± 0.74

4.55 ± 0.58

4.18 ± 0.85

0.10

Thalamus (right)

7.35 ± 0.92

7.48 ± 0.86

7.65 ± 0.99

0.18

Thalamus (left)

7.26 ± 0.84

7.28 ± 1.08

7.26 ± 1.15

0.13

Caudate (right)

3.90 ± 0.50

3.86 ± 0.60

3.82 ± 0.74

0.12

Caudate (left)

3.85 ± 0.46

3.65 ± 0.53

3.60 ± 0.58

0.08

STN (right)

0.112 ± 0.018

0.108 ± 0.019

0.104 ± 0.019

0.09

STN (left)

0.106 ± 0.02

0.103 ± 0.017

0.101 ± 0.01

0.10

  1. PD Parkinson’s disease, TIV total intracranial volume, SN substantia nigra, STN sub-thalamic nucleus.