Table 3 Demographic and clinical characteristics of the three study populations.

From: Texture-based markers from structural imaging correlate with motor handicap in Parkinson’s disease

 

Healthy controls (N = 32)

Patients with early-stage PD (N = 39)

Patients with late-stage PD (N = 37)

p

Sex (M/F)

18/14

22/17

22/15

0.30*

Age (years)

61.6 ± 10.8

63 ± 10.4

60.75 ± 9.6

0.40**

Disease duration (years)

–

0.45 ± 0.46

8.5 ± 3.9

 < 0.0001#

Hoehn–Yahr score (OFF)

–

2 (0–3)

2.5 (1–5)

 < 0.0001#

MDS-UPDRS 1

–

8.25 ± 5.70

10.2 ± 4.9

0.02#

MDS-UPDRS 2

–

5.66 ± 4.09

17.8 ± 7.16

 < 0.0001#

MDS-UPDRS 3 (OFF)

–

17.15 ± 7.40

45.42 ± 16.38

 < 0.0001#

MDS-UPDRS 4

–

0

9.0 ± 3.7

–

MDS-UPDRS total

–

32.05 ± 12.94

78.86 ± 24.44

 < 0.0001#

  1. M male, F female, PD Parkinson’s disease, MDS-UPDRS Movement Disorders Society-Unified Parkinson's Disease Rating Scale, OFF off-treatment.
  2. *Pearson’s Chi-squared test. **ANOVA. #Mann–Whitney test.
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