Figure 1

Trends of atherosclerotic burden and vulnerable plaque components by modifiable risk factors, maximum stenosis, familial history of premature CAD, sex, age, renal function and carotid side (univariate analysis). NWI normalized wall index, CAD coronary artery disease, LRNC lipid-reach necrotic core, CAP fibrous cap, IPH intraplaque hemorrhage, RF risk factors, EGFR estimated glomerular filtration rate. Bars are the median value. Kruskal–Wallis test was used to test differences, with Bonferroni correction for multiple comparisons; ***p < 0.001; **p < 0.01; *p < 0.05.