Figure 4
From: Discovery of a new class of integrin antibodies for fibrosis
Discovery a set of antibodies with strong blocking activities against both human and mouse αv integrins. (A) Titration of Ab-29, Ab-30, Ab-31, Ab-32, and Ab-33 for their binding to CHOK1-human αvβ1, αvβ6, and α5β1 stable cell lines in CELISA assays. (B) EC50 of Ab-29, Ab-30, Ab-31, Ab-32, and Ab-33 in CELISA assays, as well as their IC50 in human and mouse AlphaLISA integrin blocking assays.
