Figure 1

Map of human gut microbiome metagenomes analyzed. Analyzed microbial metagenomes originated from the following populations/datasets: Industrial North American/European—Human Microbiome Project25 (Missouri, Texas—USA, n = 50), Oklahoma3 (USA, n = 21), Northern Europe27(n = 43) ; Industrial Central/East Asia—China21 (Guandong Province, China, n = 38), Tokyo20 (Japan, n = 32), Astana24 (Kazakhstan, n = 26); Pastoral—Mongolia23 (Khentii Province, n = 50); Rural Agriculturalist—Burkina Faso (n = 90), Madagascar26 (n = 50); Hunter Gatherer—Matses3 (Peru, n = 25), Hadza22 (Tanzania, n = 26).