Table 1 Patient characteristics of all analyzed conduits.

From: Screening for potential targets to reduce stenosis in bioprosthetic heart valves

Patient

Gender

Diagnosis

Implant

Age at implantation

Duration of implantation

Reason for explantation

Methods applied

NGS 1

Male

PV Agenesis

Hancock

2 m

3 y 5 m

Stenosis

W

NGS 2

female

TAC

Contegra

3 m

2 m

Insufficiency

W

NGS 3

Female

Hemitruncus, VSD, PS, PFO

Contegra

2 m

6 m

Insufficiency

W

NGS 4

Male

TOF, PA

Hancock

19 y 4 m

4 y 8 m

Stenosis

L, W

NGS 5

Male

DOLV, MGA, PS

Contegra

2 y 7 m

11 y 11 m

Stenosis

L, W

NGS 6

Male

TAC, ASD

Hancock

2 m

5 y 0 m

Stenosis, Insufficiency

L, W

NGS 7

Female

VSD, PA

Melody in Homograft

18 y 5 m

4 y 8 m

Stenosis

L, W

NGS 8

Male

TAC, ASD

Hancock

5 y 2 m

2 m

Endocarditis

L

NGS 9

Male

AS, Ross-Procedure

Contegra

1 y 10 m

9 y 1 m

Stenosis, Endocarditis

L, W

NGS 10

Male

d-TGA, VSD

Hancock

5 y 10 m

14 y 10 m

Stenosis

L, W

NGS 11

Female

DORV, VSD, PA

Hancock

11 m

6 y 7 m

Stenosis

L, W

Histo 1

Male

DORV, TOF

Hancock

5 m

9 m

Stenosis

Histology

Histo 2

Male

PA, VSD

Hancock

9 m

9 m

Stenosis

Histology

Histo 3

Female

DORV, TOF

Hancock

11 m

9 m

Stenosis

Histology

Histo 4

Male

DORV, TGA

Hancock

3 m

1 y 2 m

Stenosis

Histology

Histo 5

Female

DORV

Hancock

1 y 3 m

1 y 5 m

Stenosis

Histology

Histo 6

Male

PA, VSD

Hancock

1 y 2 m

3 y 1 m

Stenosis

Histology

Histo 7

Male

TOF, PS

Hancock

7 m

5 y 8 m

Stenosis

Histology

Histo 8

Male

TGA, VSD

Hancock

6 y 10 m

15 y 6 m

Stenosis

Histology

Histo 9

Female

TOF

Contegra

1 y 5 m

1 y 2 m

Stenosis

Histology

Histo 10

Male

PA, VSD

Matrix P

1 m

10 m

Stenosis

Histology

Histo 11

Male

Dysplastic AV

Homograft

41 y 1 m

9 y 5 m

Stenosis

Histology

  1. AS, aortic stenosis; ASD, atrial septal defect; AV, aortic valve; d-TGA- dextro-transposition of the great arteries; DOLV, double outlet left ventricle; DORV, double outlet right ventricle; L, leaflet; MGA, malposition great arteries; PA, pulmonary atresia; PFO, patent foramen ovale; PS, pulmonary stenosis; PV, pulmonary valve; TAC, truncus arteriosus communis; TGA, transposition of the great arteries; TOF, tetralogy of Fallot; VSD, ventricular septal defect; W, wall; NGS, next generation sequencing.
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