Figure 5 | Scientific Reports

Figure 5

From: Integrin α2β1 plays an important role in the interaction between human articular cartilage-derived chondrocytes and atelocollagen gel

Figure 5

BTT 3033, a selective integrin inhibitor alters cell proliferation and MMP expression in AC(+) group. Expression of collagen-binding integrins (A), cell cycle-related factors (C), and MMP family (D) in the presence of BTT 3033, a selective inhibitor of α2β1 integrin, in cells cultured with atelocollagen gel. Normalized expression relative to cells cultured in the absence of BTT 3033 is shown (A,C,D). (B) DNA content relative to cells cultured in the absence of BTT 3033 is shown. A representation of three independent experiments, each with three subjects is shown. *p < 0.05, **p < 0.01.

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